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Home - Products - Cell Cycle/DNA Damage - Potassium Channel - A2764 dihydrochloride

A2764 dihydrochloride

CAS No. 861038-72-4

A2764 dihydrochloride( —— )

Catalog No. M21057 CAS No. 861038-72-4

A2764 dihydrochloride is a highly selective inhibitor of TRESK.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 53 Get Quote
10MG 87 Get Quote
25MG 156 Get Quote
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Biological Information

  • Product Name
    A2764 dihydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    A2764 dihydrochloride is a highly selective inhibitor of TRESK.
  • Description
    A2764 dihydrochloride is a highly selective inhibitor of TRESK.
  • In Vitro
    A2764 (100 μM) inhibits the background K+ current by 42.8±11.5% when it applies to the oocytes expressing mTRESK.A2764 (100 μM) shows an improvedinhibitory potency for activated channel with an IC50 of activated channel in ionomycin-activated mTRESK current.The subsequent application of A2764 strongly inhibits the current (77.8±3.5%).A2764 (100 μM) inhibits the current of TRESK under resting conditions and in the activated state by 42.8±11.5% and 77.8±3.5%, respectively.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Potassium Channel
  • Recptor
    mTRESK channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    861038-72-4
  • Formula Weight
    351.7
  • Molecular Formula
    C15H21Cl3N2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:41.67 mg/mL?(118.48 mM)
  • SMILES
    CCN(CC)CCOc1ccc(Cl)c2cccnc12.Cl.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Chemically Modified Derivatives of the Activator Compound Cloxyquin Exert Inhibitory Effect on TRESK (K2P18.1) Background Potassium Channel.[J]. Molecular pharmacology 2019.
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